Quantitative Cell Biology of the Nucleus

Research Lines

The role of telomeres in meiosis

 Unraveling genetic stability and fertility

Investigating how telomeres influence chromosome behavior during meiosis, shaping genetic stability, fertility, and the prevention of age-related diseases.

AI-driven mutation prediction

  Shaping the future of reproductive health

Using cutting-edge artificial intelligence to predict mutations that impact gametogenesis, offering new insights into fertility treatments and genetic disorders.

. . . Decoding the dance of Chromosomes . . . 

 

In our lab, we study the molecular basis of chromosome dynamics during gametogenesis through a combination of computational tools and experimental benchwork. We develop methods to analyze chromosome movement, particularly in the fission yeast Schizosaccharomyces pombe, and conduct hands-on experiments to validate our findings. We also created the web application ChroMo, which helps us gain deeper insights into meiotic prophase in yeast, allowing us to identify previously undetectable phenotypes. Our research extends to both computational and experimental approaches to investigate other key stages of gametogenesis, such as telomere bouquet formation, spindle assembly, and detecting aneuploidies

Do you want to join us?


We are a young and dynamic team of researchers dedicated to understanding the molecular mechanisms that regulate chromosome movement. 


If you are a student or researcher passionated for science, we would love to hear from you! We are looking for curious and motivated individuals who want to explore the fascinating world of gametogenesis and contribute to innovative projects.

 

Are you ready to join us? 

Reach out and discover how you can be part of our team!